Second chance: experimental CAR t therapy offered to patients with no other options

NCT ID NCT05776134

AVAILABLE Disease control Sponsor: Kite, A Gilead Company Source: ClinicalTrials.gov ↗

First seen Apr 26, 2026 · Last updated May 01, 2026 · Updated 1 time

Summary

This study gives patients with mantle cell lymphoma or acute lymphoblastic leukemia access to a CAR T-cell therapy (brexucabtagene autoleucel) that didn't pass commercial quality checks but is still considered safe enough for use. Participants must have their own batch of the therapy that meets the study's stricter release criteria. The goal is to provide treatment when no commercial option is available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Avera Cancer Institute
AVAILABLE

Sioux Falls, South Dakota, 57105, United States
Banner MD Anderson Cancer Center
AVAILABLE

Gilbert, Arizona, 85234, United States
Baylor University Medical Center
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Dallas, Texas, 75246, United States
Beth Israel Deaconess Medical Center
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Boston, Massachusetts, 02215, United States
City of Hope
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Duarte, California, 91010, United States
Cleveland Clinic
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Cleveland, Ohio, 44195, United States
Colorado Blood Cancer Institute
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Denver, Colorado, 80218, United States
Dana Farber Cancer Institute - Chestnut Hill
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Boston, Massachusetts, 02215, United States
Fox Chase Cancer Center
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Philadelphia, Pennsylvania, 19111, United States
Fred Hutchinson Cancer Center
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Seattle, Washington, 98109, United States
Hospital of the University of Pennsylvania
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Philadelphia, Pennsylvania, 19104, United States
Houston Methodist Hospital
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Houston, Texas, 77030, United States
Huntsman Cancer Institute, University of Utah
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Salt Lake City, Utah, 84112, United States
Icahn School of Medicine at Mount Sinai
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New York, New York, 10029, United States
John Theurer Cancer Center at Hackensack University Medical Center
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Hackensack, New Jersey, 07601, United States
MD Anderson Cancer Center
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Houston, Texas, 77030, United States
Massachusetts General Hospital
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Boston, Massachusetts, 02114, United States
Mayo Clinic
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Rochester, Minnesota, 55902, United States
Mayo Clinic Jacksonville
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Jacksonville, Florida, 32224, United States
Medical College of Wisconsin
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Milwaukee, Wisconsin, 53227, United States
Methodist Healthcare System of San Antonio dba Methodist Hospital
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San Antonio, Texas, 782229, United States
Montefiore Medical Center (MMC)
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The Bronx, New York, 10467, United States
Northside Hospital
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Atlanta, Georgia, 30342, United States
Northwestern Memorial Hospital
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Chicago, Illinois, 60611, United States
Oregon Health & Science University
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Portland, Oregon, 97239, United States
Roswell Park Cancer Institute
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Buffalo, New York, 14263, United States
Sarah Canon Research Institute
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Nashville, Tennessee, 37203, United States
St. Luke's Cancer Institute
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Boise, Idaho, 83712, United States
Tennessee Oncology
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Nashville, Tennessee, 37203, United States
The Ohio State University
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Columbus, Ohio, 43201, United States
The University of Kansas Medical Center
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Westwood, Kansas, 66205, United States
UNC Hospitals, The University of North Carolina at Chapel Hill
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Chapel Hill, North Carolina, 27514, United States
UPMC Hillman Cancer Center
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Pittsburgh, Pennsylvania, 15232, United States
University of Alabama at Birmingham
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Birmingham, Alabama, 35234, United States
University of Maryland Cancer Center
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Baltimore, Maryland, 21201, United States
University of Michigan
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Ann Arbor, Michigan, 48109, United States
University of Nebraska Medical Center
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Omaha, Nebraska, 68198, United States
University of Rochester Medical Center
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Rochester, New York, 14642, United States
Vanderbilt-Ingrim Cancer Center
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Nashville, Tennessee, 37232, United States
Virginia Commonwealth University
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Richmond, Virginia, 23298, United States
Washington University School of Medicine- Siteman Cancer Center
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St Louis, Missouri, 63110, United States
Weill Cornell Medicine - NewYork-Presbyterian Hospital
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New York, New York, 10021, United States
West Virginia University
AVAILABLE

Morgantown, West Virginia, 26506, United States
Winship Cancer Institute
AVAILABLE

Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.

ACUTE LYMPHOBLASTIC LEUKEMIA MANTLE CELL LYMPHOMA