Can video games help Huntington's patients move and think better?
NCT ID NCT06807892
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of exercise-video game (exergame) programs for people with Huntington's disease. One program mixes physical and mental exercises together, while the other does them separately. Researchers want to see which approach improves balance, thinking, and daily life. The trial will include 40 adults with early-stage Huntington's disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- exergame-based cognitive-motor rehabilitation
- What this could lead to
- If it works, this could point toward a better way to manage movement and thinking problems in Huntington's disease.
- What could go wrong
- This is a small, early-stage study with only 40 people, so results may not apply widely. The benefit over standard care is uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults at inclusion * Huntington's disease diagnosed and confirmed by genetic analysis * Patient with stage 1-2 HD with a motor UHDRS score ≥ 5 and a CFT between 6 \< CFT ≤ 13 * Patient with written informed consent or third-party consent * Affiliated or beneficiary of a social security scheme Exclusion Criteria: * Poor understanding of the French language * Participation in interventional research modifying management * History likely to interfere with cognition (established stroke, sequelae of traumatic brain injury, active epilepsy, learning disorders, alcohol dependence syndrome, drug use, psychiatric disorders), severe cognitive deficit (MMSE \<16), clinically significant pathological condition which, in the investigator's opinion, could interfere with the subject's safety or the evaluation of study results * Pregnant or breast-feeding women * Persons deprived of their liberty by administrative or judicial decision * Persons under compulsory psychiatric care
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Angers University hospital
RECRUITINGAngers, France
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