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Which exercise works best for women with heart failure? a new trial seeks answers

NCT ID NCT07662876

Symptom relief Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of exercise—moderate-intensity aerobic training and high-intensity interval training (HIIT)—in women aged 40-70 with stable heart failure. Over 12 weeks, researchers measure how each program affects functional capacity (e.g., walking distance) and quality of life. The goal is to identify which exercise approach offers greater benefits for this specific group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
exercise (moderate-intensity aerobic training vs high-intensity interval training)
What this could lead to
If one exercise type proves better, it could guide tailored cardiac rehab programs for women with heart failure, improving their daily function and well-being.
What could go wrong
This is a small, early-stage study (64 participants) focused on short-term outcomes. Results may not apply to all heart failure patients, and exercise carries inherent risks for this population.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 64 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 70 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged 40-70 years, diagnosed with Stable Heart Failure (NYHA class II or III). * Clinically stable patients referred for exercise-based cardiac rehabilitation by the physician. * Able to perform exercise testing (able to walk 150 meters on the six-minute walk test) before starting the program. * Women willing to participate and provide informed consent. Exclusion Criteria: * Unstable Heart failure or myocardial infarction (\< 4 weeks). * Severe arrhythmias, uncontrolled hypertension, or ongoing chest pain during exercise. * Orthopedic, neurological, or cognitive limitations preventing safe exercise participation. * Any medical contraindication to exercise testing. * Refusal or inability to provide informed consent or comply with the rehabilitation program.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Heart failure

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Riphah International University

    Islamabad, Fedral, 44000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.