Which exercise best trims belly fat and heart risk?
NCT ID NCT00917917
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This trial tests whether the type of physical activity—resistance, endurance, or a mix—combined with a low-calorie diet can reduce belly fat and cardiovascular risk in people with metabolic syndrome. Adults aged 50-70 with metabolic syndrome are randomly assigned to one of three exercise groups, all following the same restrictive diet. After an initial training period, participants follow the program at home and are monitored for a year. The main goal is to see which exercise approach most effectively shrinks abdominal circumference, a key marker of metabolic syndrome.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A combined program of physical activity (resistance, endurance, or both) and a restrictive diet (500-700 kcal/day)
- What this could lead to
- If successful, this could identify the most effective type of exercise to pair with diet for reducing belly fat and cardiovascular risk in people with metabolic syndrome, potentially improving long-term health outcomes.
- What could go wrong
- The trial is relatively small and the results may not apply to everyone. Long-term adherence to diet and exercise is often challenging, and the benefits may diminish once participants return to their normal routines.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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150 people
The number who actually took part.
- Start date
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May 2009
- Finished
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Oct 2011
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 50-70 years old from both sexes * with metabolic syndrome * affiliated to a social security system * able to practice maximal physical exercises based on VO2 max * able to sign inform consent Exclusion Criteria: * recent (6 month) major health conditions and patients with recurrent health problems (1 per year) * patients who are not capable to perform VO2 max without abnormalities * dyserection treated patients * patients with insufficient comprehensive ability to feel questionnaire and/or to change habits
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Clermont-Ferrand
Clermont-Ferrand, 63003, France
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