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Exercise plus taurine may fight hidden muscle fat in older women

NCT ID NCT07730255

Disease control Sponsor: University of Sao Paulo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial tests whether 16 weeks of supervised exercise, with or without daily taurine supplements, can reduce fat stored inside the muscles of women aged 60–75 with obesity. Researchers will use MRI scans, muscle biopsies, and blood tests to measure changes in muscle composition, physical function, and gene activity. The goal is to see if this combination can improve muscle health and mobility without medication.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
taurine dietary supplement and concurrent exercise training
What this could lead to
If it works, this could point toward a non-drug strategy to reduce harmful fat inside muscles and improve mobility in older women with obesity.
What could go wrong
This is a small, early-stage trial with only 44 participants. The results may not apply to men or people with different health profiles, and taurine may cause digestive side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 44 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 75 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female, * 60 and 75 years of age, * Body mass lower than 120 kg, * Be sedentary (not having engaged in physical exercise for at least 3 months), and * Body Mass Index between 30 and 40 kg/m². Exclusion Criteria: * alcohol consumption, * smoking, * infectious and contagious diseases, * chronic kidney diseases, * undergoing weight loss treatment, and * presenting a score ≤13 on cognitive screening using the Mini-Mental State Examination (MMSE).

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Conditions

The condition(s) this trial relates to.

Motor Activity Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity (bmi>30)

Contacts and locations

Locations

  • Escola de Educação Física e Esporte de Ribeirão Preto, Ribeirão Preto, São Paulo.

    Ribeirão Preto, São Paulo, 14040-900, Brazil

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