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New exercise study targets muscle weakness in obese women

NCT ID NCT07407621

Knowledge-focused Sponsor: Universiti Sains Malaysia Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether an 8-week program of eccentric (lengthening) resistance training can improve muscle strength, nerve function, and health markers like blood sugar and cholesterol in obese, inactive women. 24 women aged 25-45 with a BMI over 23 will be assigned to either eccentric or concentric (shortening) training. The goal is to see which type of exercise leads to better muscle and metabolic adaptations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 24 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

INCLUSION CRITERIA: * Eumenorrheic women (reporting menstrual cycle between 21-35 days) * Age 25-45 y/o * BMI \> 23.0 kg/m2 * Body fat percentage \> 30% * No lower limb orthopaedic injuries * Have not participated in any structured/ unstructured weight loss intervention in the past 12 months * Sedentary lifestyle (regular exercise \<1 hour per week) * Stable body weight (loss or gain of no greater than 2 kg) * Stable medication use for six months before enrolment EXCLUSION CRITERIA: * smokers * taking supplements or medication known to affect REE (such as oral contraceptives) * severe medical conditions affecting their physical or mental health * individuals with an implanted medical device * suffer from alcohol or drug abuse * trying to conceive/ pregnant, or breastfeeding

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity Physical inactivity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Community Health

    Kepala Batas, Pulau Pinang, 13200, Malaysia

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