Exercise study seeks to unlock eating disorder clues
NCT ID NCT06213883
First seen Jun 27, 2026 · Last updated Aug 26, 2026 · Updated 2 times
Summary
This study looked at how exercise changes body image, mood, and certain blood markers in young women aged 16-25 with restrictive eating disorders. Researchers measured responses during lab-based exercise and rest. The goal is to better understand driven exercise—a common symptom—and lay groundwork for more targeted treatments.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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74 people
The number who actually took part.
- Started
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Nov 2023
- Finished
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Jul 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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16 to 25 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 16-25 * ED participants must meet full criteria for DSM-5 restrictive-spectrum eating disorders characterized by weight and shape concern, I.e., anorexia nervosa (AN); mild, moderate, or in partial remission), atypical AN, and OSFED -AN type only) * ED participants must be medically stable, and suitable for outpatient treatment * Biological Females, Assigned Female at birth * English Speaking Exclusion Criteria: * Those with a medical condition that precludes exercise (e.g., severe asthma) will be excluded for any contraindications * Biological Males, Assigned Male at birth * BMI less than 16 (over 18 years) or less than 75% expected body weight (under 18 years) * Reported intake on Eating Disorder Examination \<1000kcal daily * Current purging \>1x per day * Current regular episodes of objective binge eating (\>1x/wk) * Current self-report of loss-of control eating per the Eating Disorders Examination Interview * ED related hospitalization, partial hospitalization, or residential treatment in the past month * Any endorsed medical concerns related to physical activity (as probed in the phone screening questions regarding cardiovascular, pulmonary, or metabolic disease). * Major medical disorders (e.g., cancer, AIDS) * Physical discomfort or difficulty with blood draws * Psychotic disorders * Intellectual disabilities * Developmental disorders * Active substance use disorder * Current suicidal risk per the Ask Suicide Screening Questionnaire * Pregnancy * Psychiatric medications that have not been stable for at least 4 weeks * Acute sedatives / pain killers (e.g., benzodiazepines, opioids) and prescription stimulants (e.g., methylphenidate, amphetamines) are not permitted for the full day prior to the laboratory session. The noted short-term medication holds only apply to subjects taking the noted medications in cases used to treat ADHD or other psychiatric conditions * Resting heart rate \<50 beats per minute (assessed at screening visit) * Low blood pressure (\<90/60), (assessed at screening visit) * Daily cannabis use * History of light headedness or fainting during blood draws or physical activity * History of chest pain during physical activity * Bone, joint, cardiac, pulmonary, metabolic, or other medical conditions that may be worsened by physical activity (e.g., COPD, diabetes, hypertension) that are not currently addressed via medication or lifestyle change. * Physical disabilities that prohibit task performance (such as blindness or deafness) * Any other condition that the investigator believes might put the participant at risk for negative outcomes * Individuals with a restrictive eating disorder presentation that does not include weight and shape concern (ARFID) or that has primary binge eating (bulimia nervosa) * Indication of health risk associated with exercise on the Physical Activity Readiness Questionnaire
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of California San Francisco
San Francisco, California, 94158, United States
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University of Wisconsin-Madison
Madison, Wisconsin, 53719, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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