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Dual relief: tailored exercise eases heart and knee woes

NCT ID NCT07440914

Symptom relief Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a 12-week exercise program designed for people with both congestive heart failure and knee osteoarthritis. 94 adults took part, with half doing low-impact aerobic and strength exercises and the other half receiving standard care. The goal was to see if the tailored program could improve heart fitness, knee function, and quality of life without worsening joint pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

94 people

The number who actually took part.

Started

Jul 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with a confirmed diagnosis of CHF, classified according to the New York Heart Association (NYHA) functional classification II-III. * Radiographically confirmed diagnosis of knee OA, based on the Kellgren-Lawrence grading system (grade II-III). * Adults aged 40-80 years * Left ventricular ejection fraction (LVEF) ≤ 40% as measured by echocardiography within the last 6 months. * Patients must be on stable pharmacologic therapy for CHF for at least 4 weeks prior to enrollment. Exclusion Criteria: * Presence of severe comorbid conditions that could interfere with the study protocol or pose a risk to the patient, such as severe pulmonary disease, advanced renal or liver disease, or active malignancy. * Kellgren-Lawrence grade IV knee OA or recent knee surgery within the last 6 months. * Presence of inflammatory arthritis, such as rheumatoid arthritis or gout * Recent myocardial infarction (within the past 3 months), unstable angina, or recent coronary artery bypass graft surgery. * Any condition that contraindicates exercise participation, such as severe hypertension (BP \> 180/110 mmHg), uncontrolled arrhythmias, or severe aortic stenosis. * Significant cognitive impairment or psychiatric disorder that would interfere with adherence to the exercise protocol. * Patients already participating in regular, structured exercise programs exceeding moderate intensity (\>150 minutes per week)

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Conditions

The condition(s) this trial relates to.

congestive heart failure heart failure osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Congestive heart failure

Contacts and locations

Locations

  • 1. Behria International Hospital 2. Punjab Institute of Cardiology

    Lahore, Punjab Province, 42000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.