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Dialysis patients try exercise to fight muscle weakness

NCT ID NCT07303179

Symptom relief Sponsor: The First People's Hospital of Yunnan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a structured exercise program during dialysis sessions can improve strength, walking ability, and quality of life for people with end-stage kidney disease. About 800 patients will be randomly assigned to either dialysis plus exercise or dialysis alone. The exercise includes warm-up, resistance training, and cycling, done three times a week for two years. Researchers will track changes in walking distance, muscle strength, hospitalizations, and overall well-being.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
structured exercise rehabilitation therapy (ERT)
What this could lead to
If it works, this could lead to a standard exercise program that helps dialysis patients feel stronger, walk farther, and have a better quality of life.
What could go wrong
This is a relatively small, early-stage study. Exercise may be hard for some patients to stick with, and benefits might not be large or apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Jun 2025

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 74 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. On maintenance hemodialysis for ≥3 months. 2. Age 18-74 years. 3. Receiving adequate standard medical management. 4. Hemodialysis frequency: 3 times per week. 5. Kt/V \> 1.2. Exclusion Criteria: 1. New York Heart Association (NYHA) class IV heart failure. 2. Recent uncontrolled unstable angina. 3. Severe peripheral arterial disease or musculoskeletal disorders. 4. Walking distance \<200 meters. 5. Resting oxygen saturation \<90%. 6. Amputation or other conditions precluding exercise.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

End-stage renal disease (ESRD) Maintenance hemodialysis (MHD)

Contacts and locations

Locations

  • The First People's Hospital of Yunnan Province

    Kunming, Yunnan, 650032, China

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