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Exercise and protein: a One-Two punch against Age-Related muscle loss?

NCT ID NCT02912130

Disease control Sponsor: Liverpool Hope University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at whether combining aerobic and resistance exercise with protein supplements can improve muscle, strength, and quality of life in older adults with sarcopenia (age-related muscle loss). 110 people aged 60-90 took part. The goal was to see if this combination works better than either alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
protein supplementation, aerobic exercise, resistance exercise
What this could lead to
If it works, this could point toward a simple, drug-free way to help older adults maintain muscle and independence.
What could go wrong
This is a completed early-stage study with 110 participants, so results may not apply to everyone. Diet and exercise changes can be hard to stick with long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

110 people

The number who actually took part.

Started

Sep 2016

Finished

Dec 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and Female participants * 60 - 90 years of age * Resident in North West, England, UK * BMI 18.5-30 kg/m * Can speak and understand English * Willing to consent and follow the study procedures Exclusion Criteria: * Recent (i.e. past 3 months) or concurrent participation in any clinical trial or dietary and/or exercise intervention program * Self-reported lactose intolerance * Uncontrolled diabetes (HbA1C \>10) * Uncontrolled Hypertension (160/100) and uncontrolled hypotension (\<100 systolic) * Treatment with Beta Blockers, Calcium Channel Blockers, Digitalis, Bronchodilator, * Diuretics, Vasodilators * Current hormone therapy such as insulin, testosterone or hormone replacement therapy * History of falls/osteoporosis * Major psychological/mental illness * Medical conditions that precluded safe participation in an exercise program * Other major systemic diseases: Liver and kidney diseases, Advanced gastrointestinal disorders, Cardiovascular Diseases, Advanced chronic obstructive pulmonary disease, Advanced Rheumatoid Arthritis, Cancer

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Conditions

The condition(s) this trial relates to.

Motor Activity muscular atrophy Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Muscular atrophy Sarcopenia

Contacts and locations

Locations

  • Liverpool Hope University

    Liverpool, Merseyside, L16 9JD, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.