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Home workouts may boost cancer Patients' cell power

NCT ID NCT04558398

Knowledge-focused Sponsor: University of Nottingham Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how prostate and colorectal cancer affect mitochondria—the energy factories in cells—and whether a 4-week home exercise program could improve them. Fifteen men awaiting surgery did either resistance or high-intensity interval training at home. Researchers measured changes in mitochondrial activity and muscle function before and after the program.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

15 people

The number who actually took part.

Started

Aug 2021

Finished

Mar 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria 1. Aged 50 years and over (no upper age limit) 2. Male patients 3. Histologically confirmed malignancy, radiologically or direct visualisation leading to high clinical suspicion of cancer with planned surgical resection as treatment option (prostate or colorectal). 4. Sufficient mobility to be able to complete a home-based exercise program 5. Capacity to give informed and written consent 6. Ability to travel to the RDH to complete the assessment session Exclusion criteria 1. Current participation in a formal exercise regime 2. Inability to complete exercise training 3. Inadequate level of the English language to be able to provide consent 4. A BMI \<16.5 or \>35 kg/m2 5. Active cardiovascular disease: 1. Uncontrolled hypertension (BP \> 160/100) 2. Angina 3. Heart failure (class III/IV) 4. Significant arrhythmia 5. Right to left cardiac shunt 6. Recent cardiac event 6. Taking beta-adrenergic blocking agents 7. Cerebrovascular disease: g. Previous stroke h. Aneurysm (large vessel or intracranial) i. Epilepsy 8. Respiratory disease including: j. Pulmonary hypertension k. Significant COPD l. Uncontrolled asthma 9. Clotting dysfunction or current use of anticoagulants (eg Warfarin/Clopidogrel/ Rivaroxaban) 10. Significant musculoskeletal or neurological disorders 11. Female patients 12. Those requiring or receiving neoadjuvant chemotherapy

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal cancer Prostate cancer

Contacts and locations

Locations

  • Thomas Smart

    Derby, Derbyshire, DE22 3NE, United Kingdom

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