Can exercise really boost your metabolism? new study aims to find out
NCT ID NCT06923163
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how a 12-week running program affects energy use in 80 sedentary adults. Participants will run five times a week, with researchers measuring changes in calories burned, food intake, and activity levels. The goal is to understand why exercise doesn't always lead to the expected increase in total energy expenditure.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- aerobic exercise (running sessions, 5 times per week for 12 weeks)
- What this could lead to
- If successful, this study could help explain why exercise doesn't always lead to expected weight loss, potentially improving future obesity treatments.
- What could go wrong
- This is a small, early-stage study (80 participants) focused on healthy, sedentary adults. Results may not apply to people with medical conditions or different activity levels.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Sedentary individuals * BMI ≥ 18.5 kg/m2 Exclusion Criteria: * Individuals who have undergone major surgery in the past 6 months (excluding tooth extraction); * Individuals on long-term medication; * Individuals with metabolic and cardiovascular diseases such as diabetes, hypoglycemia, and hypertension; * Individuals with exercise-related injuries, including joint diseases and fractures; * Individuals diagnosed with infectious diseases such as HIV, tuberculosis, malaria, etc.; * Individuals with mental and neurological disorders including anorexia nervosa; * Individuals who have attempted weight loss or gain through various methods in the past three months; * Individuals in preconception, pregnancy, and lactation periods; * Individuals with autism and those with metal implants in their bodies.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
RECRUITINGShenzhen, Guangdong, China
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