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Can exercise boost walking in Parkinson's patients with muscle loss?

NCT ID NCT07165106

Symptom relief Sponsor: Ahi Evran University Education and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether adding resistance or aerobic exercise to standard rehab helps walking and muscle strength in people with Parkinson's disease who also have muscle loss (sarcopenia). 32 participants were assigned to either resistance or aerobic exercise for 6 weeks. The goal was to see improvements in mobility, gait speed, and strength.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
exercise (resistance and aerobic)
What this could lead to
If successful, this could point toward better exercise programs to improve walking and muscle function in people with Parkinson's disease and muscle loss.
What could go wrong
This is a small, completed study with only 32 participants, so results may not apply to everyone. Exercise benefits can vary widely between individuals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

Sep 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and female patients aged 40-85 years with a clinical diagnosis of Parkinson's disease. * Diagnosis of sarcopenia according to the EWGSOP2 criteria. * Hoehn \& Yahr stage 2-3. * Ability and willingness to provide written informed consent according to the approved study consent form. Exclusion Criteria: * Failure to meet diagnostic criteria for sarcopenia. * Hoehn \& Yahr stage 1 or 4. * History of malignancy. * Epilepsy. * History of cardiac pacemaker implantation. * Presence of congestive heart failure. * Orthopedic conditions affecting walking or balance. * Respiratory disorders impairing exercise capacity. * Uncontrolled hypertension. * Inability to cooperate with study procedures. * History of neuromuscular or vestibular disorders affecting gait or balance parameters. * Lack of willingness to participate in the study.

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Conditions

The condition(s) this trial relates to.

Motor Activity Parkinson disease Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Parkinson disease (disorder) Sarcopenia

Contacts and locations

Locations

  • Kırşehir Ahi Evran University

    Kırşehir, 40100, Turkey (Türkiye)

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