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Exercise program aims to boost strength in young cancer patients

NCT ID NCT07647471

Symptom relief Sponsor: Universität Duisburg-Essen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 11, 2026 · Updated 2 times

Summary

The BEPPO study is testing whether a structured exercise program can improve physical and mental health in 346 children and teens (ages 3-18) undergoing cancer treatment across 13 German centers. Participants are randomly assigned to either a 6-month exercise program (3-5 sessions per week) plus counseling, or standard care. The main goal is to improve leg strength, with secondary aims including endurance, balance, fatigue, and quality of life. The study hopes to provide evidence to make exercise a routine part of pediatric oncology care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
structured exercise program (strength, endurance, coordination, flexibility, balance) plus family-centered exercise counseling
What this could lead to
If it works, this could make exercise a standard part of pediatric cancer care, helping kids feel stronger, less tired, and better overall during treatment.
What could go wrong
This is a relatively early-stage study (not yet recruiting) and exercise may be hard to stick with during intensive treatment. Results may not apply to all children or cancer types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 346 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

3 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged ≥3 and ≤18 years * Oncological diagnosis with curative treatment intent * ≤6 weeks since cancer diagnosis (diagnosis can be initial, secondary or relapse diagnosis) * Information and consent procedures feasible in German, English or with using local site resources (e.g., interpreters or multilingual staff) * Communication with the patient is possible in German, English or with using local site resources (e.g., interpreters or multilingual staff) during the assessments and intervention * Patients insured by German statutory health insurers Exclusion Criteria: * Patients aged \<3 and \>18 years * No active medical oncological treatment (e.g., watch-and-wait strategy, surgery without ongoing oncological acute treatment at a pediatric oncology center) * Medical limitations that do not allow implementation of the study protocol * Life expectancy \< 6 months * Patients not insured by German statutory health insurers (e.g., Privatly insured patients, self-paying patients)

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Conditions

The condition(s) this trial relates to.

childhood malignant neoplasm Fatigue Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pediatric cancer patients

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    13 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Charité-Universitätsmedizin Berlin, Department of Pediatric Oncology/Hematology

    RECRUITING

    Berlin, Germany

  • Children's Hospital Amsterdamer Straße, ; Clinic for Children and Youth Medicine; Department for pediatric hematology/oncology

    RECRUITING

    Cologne, Germany

  • DIAKONEO Klinik Hallerwiese-Cnopfsche Kinderklinik Nürnberg, Department of Pediatric Hematology and Oncology

    RECRUITING

    Nuremberg, Germany

  • Klinikum der Landeshauptstadt Stuttgart, Zentrum für Kinder-, Jugend- und Frauenmedizin, Pädiatrie

    RECRUITING

    Stuttgart, Germany

  • Pädiatrische Hämatologie und Onkologie, Zelltherapie Zentrum für Kinder- und Jugendmedizin Eine Kooperation der München Klinik und des TUM Klinikums

    RECRUITING

    München, Germany

  • University Hospital Cologne, Department of Pediatric Oncology and Hematology, Children's Hospital

    RECRUITING

    Cologne, Germany

  • University Hospital Essen, Department of Pediatric Hematology/Oncology, Center for Child and Adolescent Medicine, Clinic for Pediatrics III

    RECRUITING

    Essen, Germany

  • University Medical Center Ulm, Department of Pediatrics and Adolescent Medicine

    RECRUITING

    Ulm, Germany

  • University of Bonn Medical Center, Department of Pediatric Hematology/Oncology,

    RECRUITING

    Bonn, Germany

  • Universitätsklinikum Hamburg-Eppendorf, Department of Pediatric Hematology and Oncology, Hubertus Wald Tumor Center, University Cancer Center Hamburg

    RECRUITING

    Hamburg, Germany

  • Universitätsklinikum Jena, Klinik für Kinder- und Jugendmedizin

    RECRUITING

    Jena, Germany

  • Universitätsmedizin Frankfurt, Department of Pediatrics, Pediatric Oncology and Haematology

    RECRUITING

    Frankfurt, Germany

  • Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Department of Pediatric Hematology/Oncology

    RECRUITING

    Mainz, Germany

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