Exercise program aims to boost strength in young cancer patients

NCT ID NCT07647471

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

The BEPPO study is testing whether a structured exercise program can improve physical and mental health in 346 children and teens (ages 3-18) undergoing cancer treatment across 13 German centers. Participants are randomly assigned to either a 6-month exercise program (3-5 sessions per week) plus counseling, or standard care. The main goal is to improve leg strength, with secondary aims including endurance, balance, fatigue, and quality of life. The study hopes to provide evidence to make exercise a routine part of pediatric oncology care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
structured exercise program (strength, endurance, coordination, flexibility, balance) plus family-centered exercise counseling
What this could lead to
If it works, this could make exercise a standard part of pediatric cancer care, helping kids feel stronger, less tired, and better overall during treatment.
What could go wrong
This is a relatively early-stage study (not yet recruiting) and exercise may be hard to stick with during intensive treatment. Results may not apply to all children or cancer types.

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Conditions

The condition(s) this trial relates to.

childhood malignant neoplasm Fatigue Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Charité-Universitätsmedizin Berlin, Department of Pediatric Oncology/Hematology

    Berlin, Germany

  • Children's Hospital Amsterdamer Straße, ; Clinic for Children and Youth Medicine; Department for pediatric hematology/oncology

    Cologne, Germany

  • DIAKONEO Klinik Hallerwiese-Cnopfsche Kinderklinik Nürnberg, Department of Pediatric Hematology and Oncology

    Nuremberg, Germany

  • Klinikum der Landeshauptstadt Stuttgart, Zentrum für Kinder-, Jugend- und Frauenmedizin, Pädiatrie

    Stuttgart, Germany

  • Pädiatrische Hämatologie und Onkologie, Zelltherapie Zentrum für Kinder- und Jugendmedizin Eine Kooperation der München Klinik und des TUM Klinikums

    München, Germany

  • University Hospital Cologne, Department of Pediatric Oncology and Hematology, Children's Hospital

    Cologne, Germany

  • University Hospital Essen, Department of Pediatric Hematology/Oncology, Center for Child and Adolescent Medicine, Clinic for Pediatrics III

    Essen, Germany

  • University Medical Center Ulm, Department of Pediatrics and Adolescent Medicine

    Ulm, Germany

  • University of Bonn Medical Center, Department of Pediatric Hematology/Oncology,

    Bonn, Germany

  • Universitätsklinikum Hamburg-Eppendorf, Department of Pediatric Hematology and Oncology, Hubertus Wald Tumor Center, University Cancer Center Hamburg

    Hamburg, Germany

  • Universitätsklinikum Jena, Klinik für Kinder- und Jugendmedizin

    Jena, Germany

  • Universitätsmedizin Frankfurt, Department of Pediatrics, Pediatric Oncology and Haematology

    Frankfurt, Germany

  • Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Department of Pediatric Hematology/Oncology

    Mainz, Germany

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