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Home exercise program shows promise for rare movement disorder

NCT ID NCT07561359

Symptom relief Sponsor: Hospital de Clinicas de Porto Alegre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 12-week strength and functional exercise program, done at home via video calls with a physiotherapist, can improve walking, balance, and daily life in people with Hereditary Spastic Paraplegia (HSP). Twenty participants aged 16 to 70 will each experience both the exercise program and a period without it. The exercises are tailored to each person's goals and abilities, focusing on leg strength and mobility.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Individualized strength and functional exercises delivered via videoconference
What this could lead to
If it works, this could provide a safe, home-based exercise program to help people with HSP walk better and improve daily function.
What could go wrong
This is a small early-stage trial with only 20 participants, so results may not apply to everyone. The exercises are done at home, so adherence and outcomes may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2024

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of hereditary spastic paraplegia confirmed by genetic testing or clinical diagnosis with a positive family history * Age between 16 and 70 years * Independent ambulation, with or without assistive devices * Access to an electronic device (smartphone, tablet, or computer) with camera and internet connection * Stable therapeutic regimen for spasticity management (pharmacological and/or physiotherapy) for at least 6 months prior to enrollment Exclusion Criteria: * Presence of other neurological or systemic conditions causing additional motor impairment or musculoskeletal injury limiting movement * Inability to perform performance outcomes even with assistive devices * Planned or ongoing botulinum toxin injections or surgical interventions for spasticity reduction during the 12-week intervention period

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Conditions

The condition(s) this trial relates to.

hereditary spastic paraplegia Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hereditary spastic paraplegia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centro de Pesquisa Clínica do Hospital de Clinicas de Porto Alegre

    Porto Alegre, Rio Grande do Sul, 90035-003, Brazil

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