Can simple exercises ease diabetic nerve pain?
NCT ID NCT05422235
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether adding foot exercises to aerobic exercise helps people with type 2 diabetes and nerve damage in their legs. 74 participants were split into three groups: usual medical care, aerobic exercise only, or aerobic exercise plus foot exercises. The goal was to see changes in ankle stiffness, muscle strength, and nerve pain symptoms over 12 weeks of training and 12 weeks of follow-up.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- aerobic exercise and foot exercises
- What this could lead to
- If successful, this could point toward simple exercise programs that help manage neuropathy symptoms and improve leg strength in people with type 2 diabetes.
- What could go wrong
- This is a small, completed study with 74 participants, so results may not apply to everyone. Exercise programs require consistent effort and may not work for all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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74 people
The number who actually took part.
- Started
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Nov 2022
- Finished
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Mar 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Being diagnosed with Type 2 DM * Being able to walk independently * Getting at least 23 points from the mini mental test * Patients with peripheral neuropathy according to ADA criteria Exclusion Criteria: * Presence of active ulcer * Amputation history * History of lower extremity surgery * Participating in a regular exercise program in the last three months * Having a Charcot deformity * Presence of major vascular complications
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Eastern Mediterranean University
Mersin, Famagusta, 99450, Turkey (Türkiye)
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