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Exercise program shows promise for Diabetes-Related memory problems

NCT ID NCT06401733

Disease control Sponsor: National University of Singapore Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a 12-week intensive exercise program (aerobic and resistance training) in 58 adults aged 40-85 with type 2 diabetes and mild cognitive issues. The goal was to see if exercise could improve thinking, blood sugar, inflammation, and physical function. Results may help guide future exercise plans for managing diabetes and protecting brain health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

58 people

The number who actually took part.

Started

Jul 2023

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 40 to 85 * Living in the community * Diagnosed with type 2 diabetes mellitus (T2DM) * Literate in English or Mandarin * Activities of daily living (ADL)-independent * Obtain at least a score of 5 in short physical performance battery (SPPB) test Exclusion criteria: * Severe cognitive (e.g., dementia) or psychiatric disorders (e.g., schizophrenia or severe depression) * Severe hearing or vision impairments * Terminally ill medical conditions (e.g., end stage cancer), severe cardiovascular, respiratory (e.g., respiratory failure), or orthopedic conditions (e.g., freeze shoulder) * Absolute contraindications to aerobic exercise and resistance training programs (e.g., recent myocardial infarction or electrocardiography changes, complete heart block, acute congestive heart failure, unstable angina, uncontrolled hypertension) * Pregnant or breastfeeding women * Uncomfortable with video-recording of intervention sessions

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction dementia Obesity type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive dysfunction Cognitive impairment Non insulin dependent diabetes mellitus Type 2 diabetes mellitus

Contacts and locations

Locations

  • National University Polyclinic (Jurong Polyclinics)

    Singapore, Singapore, 609788, Singapore

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