Exercise study for advanced lung cancer falls short
NCT ID NCT06513663
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a program combining different types of exercise could help people with advanced lung cancer feel less tired, move better, and have a better quality of life. It was designed for adults with stage III or metastatic non-small cell lung cancer who were already on maintenance immunotherapy. However, the study was stopped early and only enrolled 2 people, so no meaningful conclusions could be drawn.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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2 people
The number who actually took part.
- Started
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Oct 2024
- Finished
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Jun 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age ≥ 18 years 2. Known diagnosis of locally advanced (stage III) or metastatic NSCLC 3. Patient is currently receiving maintenance immunotherapy for at least 1 month and planned for at least 3 additional months of therapy 1. Patients receiving maintenance therapy refers to patients with stable disease or partial response to therapy, including patients who have had a history of disease progression but are currently stable or responding to a different therapy 2. Patients previously receiving chemotherapy are eligible as long as at least one month has elapsed since completing chemotherapy. Those currently receiving chemotherapy are not eligible. 4. Patient is willing and able to participate in a supervised home-based exercise program as determined by the MOVE program a.Participants must have internet access and equipment to participate in virtual exercise 5. ECOG performance status of 0-2 Exclusion Criteria: 1. Already meeting exercise guidelines and participating in at least 150 minutes of moderate or vigorous exercise per IPAQ 2. Unable to participate in the supervised home-based exercise program as determined by the MOVE program 3. Medical co-morbidities that preclude patient from participating in supervised exercise, including but not limited to: * Advanced heart failure * Advanced respiratory disease requiring home oxygen use * Uncontrolled psychiatric disorders * History of fragility fracture
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Indiana University Health Methodist Hospital
Indianapolis, Indiana, 46202, United States
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Indiana University Melvin & Bren Simon Comprehensive Cancer Center
Indianapolis, Indiana, 46202, United States
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Sidney and Lois Eskenazi Hospital
Indianapolis, Indiana, 46202, United States
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Other studies related to the condition(s) this trial covers.
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