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Exercise during chemo: a new weapon against breast cancer?

NCT ID NCT06522971

Knowledge-focused Sponsor: Latvian Biomedical Research and Study Centre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether high-intensity interval training (HIIT) can improve how breast cancer patients respond to chemotherapy before surgery. Fifty-five patients will either follow a personalized HIIT program or maintain their usual activity level. Researchers will analyze tumor tissue and blood samples to understand the molecular changes caused by exercise.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high-intensity interval training (HIIT)
What this could lead to
If it works, this could show that adding exercise to chemotherapy improves tumor response and quality of life for breast cancer patients.
What could go wrong
This is a small, early-stage study (55 participants) focused on understanding mechanisms, not proving a new treatment. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

55 people

The number who actually took part.

Started

Aug 2022

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Primary breast cancer; stage IIA-B, IIIA-C (TNM: T1-4, N0-3, M0) at diagnosis * Diagnosis established by core needle biopsy * Age 30-65 years * Prescribed doxorubicin/cyclophosphamide-based NAC * Oral and written consent Exclusion criteria: * Cardiac pathologies * Pregnancy * Blood transfusion in the last six months * Another oncological disease * Previous chemotherapy, hormonal or X-ray treatment * Participation in another clinical trial * Currently performing more than 180 min of moderate to high intensity aerobic training per week

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer

Contacts and locations

Locations

  • Latvian Biomedical Research and Study centre

    Riga, Select One, LV1067, Latvia

More trials for these conditions

Other studies related to the condition(s) this trial covers.