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Can exercise curb teen appetite? new study investigates

NCT ID NCT05443347

Knowledge-focused Sponsor: Children's Mercy Hospital Kansas City Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how regular aerobic exercise changes appetite and metabolism in sedentary overweight teenagers. Researchers measured hunger levels and blood markers after a meal, comparing teens who exercised with those who didn't. The goal is to understand if exercise alone, regardless of weight, can improve how the body regulates appetite.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Aerobic exercise
What this could lead to
If successful, this study could help design better exercise programs for teens to improve appetite control and metabolic health.
What could go wrong
This is a small, early-stage study with only 31 participants. Results may not apply to all teens, and the exercise program may not be sustainable long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

31 people

The number who actually took part.

Started

Sep 2022

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

14 to 17 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Tanner Stage III-V, as determined via self-assessment * Non-smoking * Not currently involved in any other research study * No meds that may alter metabolism * Sedentary (\<60 min/day exercise) * Willing to participate in an exercise program Exclusion Criteria: * BMI \<5th percentile or \>99th percentile for age and sex * Weight not stable * Restrained eater (\>13 on the restraint section of the three-factor eating questionnaire; Current/past diagnosis of an eating disorder. * Self-reported medical conditions (including, but not limited to, diabetes, Crohn's disease, etc.) that may affect adherence to the protocol, exercising safely, or alter metabolism * Taking medications know to affect metabolism (e.g. thyroid medication, β-blockers, or stimulants). * Gave birth in the past 12 months or \<6 months post-lactation. * Active (\>60 min/day exercise) * Not willing to participate in an exercise program

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Conditions

The condition(s) this trial relates to.

Insulin Resistance metabolic disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Appetite Energy balance Insulin sensitivity Metabolism Obesity

Contacts and locations

Locations

  • Children's Mercy Kansas City

    Kansas City, Missouri, 64108, United States

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