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Can a brisk walk curb your appetite? new study investigates.

NCT ID NCT06849050

Knowledge-focused Sponsor: Loughborough University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at how one session of brisk walking or jogging changes appetite-related hormones and brain responses to food pictures in 40 adults with different body weights. Participants exercised for 60 minutes while wearing a mask to measure oxygen use. Researchers measured hormones like oxyntomodulin and ghrelin from blood samples and linked them to appetite and brain activity. The goal is to better understand how exercise affects eating behavior.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
acute continuous exercise (brisk walking or jogging)
What this could lead to
If successful, this could help explain how exercise influences appetite and eating behavior, potentially guiding weight management strategies.
What could go wrong
This is a small, completed observational study with only 40 participants. Results may not apply to everyone, and it does not test a treatment or long-term effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jul 2024

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Body mass index (BMI) between 18.5 - 24.9 kg/m2 and a waist circumference of ≤ 88 cm for women, and ≤ 102 cm for men or a BMI between 25 - 40 kg/m2 and a waist circumference of \> 88 cm for women, and \> 102 cm for men. BMI and waist circumference thresholds vary amongst ethnicities. People with a South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family background are prone to central adiposity and their cardiometabolic risk occurs at a lower BMI. Therefore, the following BMI and waist circumference thresholds will be applied for people of South Asian, other Asian, Black African and African-Caribbean ethnicity: (1) BMI 18.5 kg/m2 to 23 kg/m2 and waist circumference of \< 90 cm for men and \< 80 cm for women; (2) BMI 23.1 kg/m2 to 40 kg/m2 and waist circumference of ≥ 90 cm for men and ≥ 80 cm for women. * Normally consumes three meals a day * Able to walk continuously for 1 hour on a treadmill * Weight stable for 3 months (\< 3kg change in weight) * Regular menstrual cycle for the last 6 months (people taking the combined contraceptive pill are eligible for the study) * Able to undergo a 45-minute MRI scan Exclusion Criteria: * Smokers (vaping is considered smoking in this study) * Known medical conditions (e.g. diabetes, heart condition) * Taking any medication which may affect the study outcomes (e.g. liraglutide, semaglutide, insulin, steroids, anti-psychotics) * Clinically diagnosed eating disorder * Previous bariatric surgery (e.g. gastric bypass, gastric band, sleeve gastrectomy) * Food allergies or intolerances, or severe dislikes to study foods * Pregnant or breastfeeding * Have recently donated blood (within eight weeks of visits 2 and 3).

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Conditions

The condition(s) this trial relates to.

Motor Activity Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity Overweight

Contacts and locations

Locations

  • Loughborough University

    Loughborough, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.