Can a simple walk predict vascular disease? new study investigates
NCT ID NCT07637396
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This observational study will look at how exercise changes blood flow in the legs of people with or at risk for peripheral arterial disease (PAD). About 85 participants will walk for 6 minutes and have their ankle-brachial index (ABI) measured before and after. The goal is to see if exercise testing can better predict vascular disease and its impact on quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors use exercise testing to better predict and manage peripheral arterial disease.
- What could go wrong
- This is an early observational study with only 85 participants, so results may not apply to everyone. It is not testing a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 85 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
recruited from local outpatient rehabilitation, vascular, and internal medicine clinics
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * individuals over 65 years of age * individuals aged 50-64 with a risk factor for atherosclerosis including diabetes mellitus, history of smoking, hyperlipidemia, hypertension, or family history of peripheral arterial disease (PAD) * individuals aged 18-50 with diabetes mellitus and one additional risk factor for atherosclerosis as noted above, or * individuals with known atherosclerotic disease in another vascular bed including the coronary, carotid, subclavian, renal, or mesenteric artery stenosis, and individuals with known PAD Exclusion Criteria * contraindications to brachial and/or ankle pressure measurement including history of deep vein thrombosis * lymphedema of the arms or legs * history of mastectomy or current leg ulceration preventing placement of a blood pressure cuff around the lower leg * an inability to lie in a supine position for 15 min * self-reported inability to walk for 6 minutes * severe cardiac or pulmonary disease limiting exercise * inability to obtain a Dopplerable pulse * noncompressible arteries (ABI \>1.4) * those unable to consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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LSU Health Shreveport
Shreveport, Louisiana, 71130, United States
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