Can exercise improve knee joint health in women with osteoarthritis?
NCT ID NCT06173193
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how a mix of step-aerobic and resistance training affects the knee joint in postmenopausal women with mild knee osteoarthritis. 103 women were split into two groups: one did the special exercise program, and the other followed standard home exercises. Researchers used advanced imaging to measure changes in cartilage and bone over 8 months of exercise and a 12-month follow-up.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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103 people
The number who actually took part.
- Started
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Jun 2023
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 to 75 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * voluntary women 55-75 years of age. * no history of any illness for which exercise is contraindicated or that would limit participation in the exercise program. * knee pain during the last 12 months. * willingness and voluntarily signed informed consent to undergo testing and intervention procedures with all of its aspects. * weight-bearing knee x-rays show radiographic Kellgren-Lawrence grade 1-2 OA in one or both tibiofemoral joints. Exclusion Criteria: * body-mass index over 35 kg/m2. * knee instability or trauma that would jeopardize the training. * inflammatory joint disease. * intra-articular steroid injections in the preceding 12 months in the knee.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Jyväskylä
Jyväskylä, 40014, Finland
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