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Exercise may alter breast tissue markers in Dense-Breasted women

NCT ID NCT03657628

First seen Jan 05, 2026 · Last updated Jun 19, 2026 · Updated 26 times

Summary

This pilot study tests whether a 12-week exercise program can change markers in breast tissue and blood of premenopausal women with dense breasts. Dense breast tissue is linked to higher breast cancer risk. The study involves 60 physically inactive women who will do strength training and aerobic exercise. Researchers will measure changes in cell growth markers and inflammation-related substances to see if exercise might lower cancer risk.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

exercise program (strength training and aerobic exercise)

What this could lead to

If it works, this could show that exercise changes breast tissue in ways that might lower breast cancer risk for women with dense breasts.

What could go wrong

This is a small, early pilot study with only 60 participants. It looks at tissue markers, not actual cancer outcomes, so any link to cancer prevention is uncertain.

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.