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Can a workout fight breast cancer cells? new study investigates

NCT ID NCT07439458

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how a single session of aerobic exercise—either moderate or high intensity—affects breast cancer cells in the lab. Researchers will take blood from breast cancer survivors before and after exercise, then see if that blood slows the growth of breast cancer cells. They will also measure proteins released during exercise that might fight cancer. The goal is to understand which type of exercise might be best for cancer survivors.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
aerobic exercise (high or moderate intensity)
What this could lead to
If successful, this could help identify the best exercise type and intensity to potentially slow breast cancer cell growth in survivors.
What could go wrong
This is a small, early-stage study (40 people) looking at lab effects, not patient outcomes. Results may not translate to real-world cancer control or apply to all breast cancer types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2024

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria (intervention group): * Reproductive age (premenopausal); * Diagnosis of Stage II-III Triple-Negative Breast Cancer (TNBC) (negative for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2)); * Timeframe of 3 to 9 months after completion of surgery, adjuvant chemotherapy, radiation therapy, and/or immunotherapy; * Physician-certified (cardiologist) physical fitness for exercise testing, supported by echocardiography (ECHO). Inclusion Criteria (control group): * Reproductive age (premenopausal); * No current or prior diagnosis of any type of cancer; * Matched by age, body constitution, and physical fitness to the breast cancer participant group. Exclusion Criteria: * Pregnancy; * Autoimmune diseases (e.g., thyroiditis, inflammatory bowel disease, atopic dermatitis, etc.); * Endocrine disorders (e.g., metabolic syndrome, diabetes); * Cardiovascular diseases; * Diagnosis of any other type of oncological disease; * Any condition for which physical activity is contraindicated (e.g., asthma, COPD, spinal disc herniation, severe iron deficiency anemia).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Laboratory of Sports and Nutrition Research

    RECRUITING

    Riga, Dzirciema Street 16, LV1007, Latvia

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