Exercise might help stroke survivors find their words again
NCT ID NCT06185023
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a high-intensity exercise program is safe and helpful for people with aphasia (trouble speaking or understanding language) after a stroke. Twelve stroke survivors took part in either a low-intensity or high-intensity exercise program. Researchers measured changes in language ability, thinking skills, and physical fitness to see if exercise could boost recovery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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12 people
The number who actually took part.
- Started
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Dec 2023
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * aphasia following single or multiple ischemic or hemorrhagic stroke; * at least 6 months from the last stroke; * proficient in English before the stroke; * at least 8 years of education; * between the ages of 18 and 80; * independent with ambulation without a device (single-point cane accepted); * medically stable with no contraindications to participate in regular physical exercise as determined by the patient's own primary care provider or other treating provider. Exclusion Criteria: * prior history of dementia, neurologic illness (other than stroke), or substance abuse; * significant visual or hearing disabilities (e.g., neglect, uncorrected visual or hearing loss) that interfere with testing; * per self-report uncontrolled cardiorespiratory and/or metabolic disorders incompatible with exercise.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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California State University East Bay
Hayward, California, 94542, United States
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University of California Berkeley
Berkeley, California, 94720, United States
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University of California San Francisco
San Francisco, California, 94143, United States
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University of San Francisco
San Francisco, California, 94118, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can hearing your own voice rewire speech after a stroke?
- Brain implant may turn thoughts into speech for people with aphasia
- Zapping the brain to restore speech after stroke?
- Can exercise boost reading recovery in stroke survivors?
- Can training the brain to think about words boost recovery from stroke-related aphasia?
- Can an AI app give a voice to brain tumor patients?