Stent showdown: which Drug-Coated device keeps heart arteries open longer?
NCT ID NCT00960648
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study looked at over 3000 people with coronary artery disease to compare two types of drug-eluting stents: everolimus-eluting (Xience/Promus) and sirolimus-eluting (Cypher). The goal was to see which one better prevents major heart problems like heart attacks or the need for repeat procedures. Researchers tracked patients for several years to measure safety and long-term effectiveness in real-world use.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- drug-eluting stents (everolimus-eluting stent and sirolimus-eluting stent)
- What this could lead to
- If successful, this could confirm that everolimus-eluting stents are as safe and effective as sirolimus-eluting stents for treating blocked heart arteries.
- What could go wrong
- This is a completed registry study, not a randomized trial, so results may be less definitive. Stents carry risks like blood clots or re-narrowing of the artery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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3,056 people
The number who actually took part.
- Started
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Apr 2008
- Finished
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Jan 2014
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Approximately 4000 patients derived from a population of patients receiving percutaneous coronary intervention for ischemic heart disease will be enrolled in the present registry.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The patient agrees to participate in this study by signing the informed consent form. * Alternatively, a legally authorized patient representative may agree to the patient's participation in this study and sign the informed consent form. Exclusion Criteria: * There are no exclusion criteria for this registry.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chonbuk National University Hospital
Iksan, South Korea
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Chungbuk National University Hospital
Cheongju-si, South Korea
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Dankook University Hospital
Cheonan, South Korea
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Gachon Kil Medical Center
Inchon, South Korea
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Gangnam Severance Hospital
Seoul, South Korea
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Gyeongsang National University Hospital
Jinju, South Korea
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Inje University Ilsan Paik Hospital
Ilsan, South Korea
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Inje University Pusan Paik Hospital
Pusan, South Korea
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Kwangju Veterans Hospital
Gwangju, South Korea
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Kyung Hee University Medical Center
Seoul, South Korea
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Presbyterian Medical Center
Jeonju, South Korea
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Samsung Medical Center
Seoul, South Korea
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Seoul National University Bundang Hospital
Seongnam, South Korea
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Seoul National University Hospital
Seoul, South Korea
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Soon Chun Hyang University Hospital Cheonan
Cheonan, South Korea
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St. Carollo Hospital
Suncheon, South Korea
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Wonkwang University Hospital
Iksan, South Korea
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Yonsei University Medical Center
Seoul, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can heart stent patients go home in 6 hours?
- Can AI read heart scans to predict the next heart attack?
- Can a new drug cool the hidden inflammation that fuels heart disease?
- New CT scanner aims to cut unnecessary heart procedures
- Heart bypass surgeons test which vein layout keeps grafts open
- A soft patch that watches your heart beat in real time