Sound waves vs. tremors: new registry tracks Long-Term results
NCT ID NCT04991831
First seen Mar 23, 2026 · Last updated Jun 23, 2026 · Updated 15 times
Summary
This registry follows 50 people with tremor-dominant Parkinson's disease who have undergone a focused ultrasound thalamotomy. The procedure uses sound waves to target a small area in the brain that causes tremors. The goal is to collect long-term safety data and measure how well the treatment controls tremors over time.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Email: •••••@•••••
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Cleveland Clinic Foundation
RECRUITINGCleveland, Ohio, 44195, United States
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Miami Neuroscience Institute Baptist Health
RECRUITINGMiami, Florida, 33176, United States
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Miami Valley Hospital
RECRUITINGFairborn, Ohio, 45324, United States
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Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Novant Health Brain & Spine Surgery
RECRUITINGHuntsville, North Carolina, 28708, United States
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Rush University
RECRUITINGChicago, Illinois, 60612, United States
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University of Dundee
RECRUITINGDundee, Scotland, DD1 9SY, United Kingdom
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Weill Cornell Medicine
RECRUITINGNew York, New York, 10065, United States
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
focused ultrasound (Exablate Neuro system)
What this could lead to
If successful, this could confirm that focused ultrasound thalamotomy is a safe and effective long-term option for controlling severe tremors in Parkinson's disease.
What could go wrong
This is an observational registry, not a controlled trial, so it cannot prove the treatment works better than alternatives. Long-term side effects or loss of tremor control are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.