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Aggressive chemo combo shows promise for rare bone cancer that has spread

NCT ID NCT03011528

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 31 times

Summary

This study tested a more intense chemotherapy plan for people aged 2 to 50 with Ewing sarcoma that has spread to bones or bone marrow (not just lungs). The goal was to see if this approach could help more patients become cancer-free for at least 18 months. 45 participants received a strong induction chemo followed by high-dose chemo with stem cell support. The trial is complete, and results help guide future treatment for this hard-to-treat group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Bordeaux Chu

    Bordeaux, 33076, France

  • CHRU Montpellier - Hôpital A. de Villeneuve

    Montpellier, 34295, France

  • CHU Grenoble Alpes

    Grenoble, 38043, France

  • CHU Hôpital Sud

    Rennes, 35056, France

  • Chr Felix Guyon

    La Réunion, Saint Denis, 97400, France

  • LILLE Centre Oscar Lambret

    Lille, 59000, France

  • LYON Centre Léon Bérard

    Lyon, 69000, France

  • Marseille Chu

    Marseille, 13000, France

  • NANCY Institut de Cancérologie de Lorraine

    Vandœuvre-lès-Nancy, 54519, France

  • Nancy Chu

    Vandœuvre-lès-Nancy, 54511, France

  • Nantes Chu

    Nantes, 44000, France

  • PARIS Institut Curie

    Paris, 75005, France

  • PARIS Trousseau

    Paris, 75012, France

  • Strasbourg Chu

    Strasbourg, 67098, France

  • TOULOUSE Institut Claudius Regaud

    Toulouse, 31059, France

  • Toulouse Chu

    Toulouse, 31059, France

  • VILLEJUIF Institut Gustave Roussy

    Villejuif, 94805, France

Conditions

Explore the condition pages connected to this study.