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New combo shows promise against tough skin cancer

NCT ID NCT05309421

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 30 times

Summary

This study tests a new drug, EVX-01, combined with the standard immunotherapy pembrolizumab in 17 adults with advanced melanoma that cannot be removed by surgery. The goal is to see if the combination shrinks tumors better than pembrolizumab alone. Participants have not received checkpoint inhibitor treatment before.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Divisione di Oncologia Medica del Melanoma

    Milan, Italy

  • Instituto Nazionale Tumori IRCCS Fondazione

    Naples, Italy

  • Melanoma Institute Australia

    Wollstonecraft, New South Wales, 2065, Australia

  • One Clinical Research

    Nedlands, Western Australia, 6009, Australia

Conditions

Explore the condition pages connected to this study.