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New eczema drug shows promise in Mid-Stage trial

NCT ID NCT07150845

Symptom relief Sponsor: Evommune, Inc. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new medicine called EVO756 in 120 adults with moderate to severe atopic dermatitis (eczema). Participants receive either the drug or a placebo to see if it safely reduces skin redness, itching, and rash. The goal is to ease symptoms, not cure the condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Chronic AD that has been present for ≥6 months * Validated-Investigator's Global Assessment score of ≥3 * EASI of ≥16 * BSA of AD involvement of ≥10% Exclusion Criteria: * Any clinically significant abnormality in laboratory evaluations, physical examinations, vital signs, or ECG at Screening * Use of certain medications * Presence of skin comorbidities or other condition(s) that may interfere with study assessments * Significant AD flare, in the opinion of the Investigator, within 4 weeks prior to study entry

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Conditions

The condition(s) this trial relates to.

atopic eczema Eczema Pruritus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atoptic dermatitis

Contacts and locations

Locations

  • Aesthetic and Dermatology Center

    Rockville, Maryland, 20850, United States

  • Center for Dermatology Clinical Research

    Fremont, California, 94538, United States

  • Clinical Trials NZ Limited

    Hamilton, NZL, 3204, New Zealand

  • DOCS Dermatology Clinical Research

    Canal Winchester, Ohio, 43110, United States

  • DS Research

    Clarksville, Indiana, 47129, United States

  • Driven Research, LLC

    Coral Gables, Florida, 33134, United States

  • Empire Dermatology

    East Syracuse, New York, 13057, United States

  • Equity Medical

    Bowling Green, Kentucky, 42104, United States

  • Equity Medical

    New York, New York, 10023, United States

  • Great Lakes Research Group, Inc.

    Bay City, Michigan, 48706, United States

  • International Clinical Research - Murfreesboro

    Murfreesboro, Tennessee, 37130, United States

  • Jordan Valley Dermatology Center

    South Jordan, Utah, 84095, United States

  • MediSearch Clinical Trials

    Saint Joseph, Missouri, 64507, United States

  • Metropolis Dermatology - Downtown Los Angeles

    Los Angeles, California, 90017, United States

  • Michigan Dermatology Institute

    Waterford, Michigan, 48328, United States

  • Momentum Clinical Research Lower Hutt

    Lower Hutt, NZL, 5010, New Zealand

  • Optimal Clinical Trials

    Auckland, NZL, 1010, New Zealand

  • Optimal Clinical Trials

    Auckland, NZL, 632, New Zealand

  • Pacific Clinical Research Network (PCRN) - Christchurch

    Christchurch Central City, Christchurch, 8013, New Zealand

  • Progressive Clinical Research

    San Antonio, Texas, 78213, United States

  • Revival Research Institute, LLC

    Troy, Michigan, 48084, United States

  • Saguaro Dermatology

    Phoenix, Arizona, 85008, United States

  • Skin Care Research - Hollywood Dermatology

    Hollywood, Florida, 33021, United States

  • Skin Care Research, LLC

    Boca Raton, Florida, 33486, United States

  • Skin Search of Rochester, Inc.

    Rochester, New York, 14623, United States

  • Skin and Beauty Center

    Pasadena, California, 91105, United States

  • Stryde Research

    Lewisville, Texas, 75056, United States

  • TrueBlue Clinical Research

    Tampa, Florida, 33609, United States

  • Wilmington Dermatology Center

    Wilmington, North Carolina, 28405, United States