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Natural oil vs. drug: which prepares the cervix better for surgery?

NCT ID NCT07641595

Symptom relief Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared evening primrose oil (a natural oil) with misoprostol (a standard drug) for softening the cervix before operative hysteroscopy. 230 women participated. Researchers measured how easily the cervix could be dilated and noted any complications like bleeding or tears. The goal was to see if the natural oil could be a gentler alternative.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
evening primrose oil and misoprostol
What this could lead to
If evening primrose oil works as well as misoprostol, it could offer a more natural option for preparing the cervix before hysteroscopy.
What could go wrong
This is a small, completed study. Results may not apply to all patients, and evening primrose oil might be less effective or cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

230 people

The number who actually took part.

Started

Nov 2024

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age range from 18-65 years * Patients need operative hysteroscopy Exclusion Criteria: * Pregnant women. * Incompetent cervix. * History of cervical operations like conization. * Contraindications for both drugs (women with bleeding disorders, consumers of anticoagulants, schizophrenic individuals receiving phenothiazine, epileptics and those on medication for antihypertension).

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cervical preparation Evening primorose oil Hysteroscopy Misoprostol

Contacts and locations

Locations

  • Sohag University

    Sohag, 82511, Egypt

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