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Zapping pancreatic tumors with heat: a Needle-Sized hope

NCT ID NCT07585032

Disease control Sponsor: Sahlgrenska University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a procedure called EUS-guided radiofrequency ablation (EUS-RFA) for people with pancreatic insulinoma, a rare tumor that causes low blood sugar. The procedure uses a thin needle passed through an endoscope to deliver heat and destroy the tumor. Researchers want to see if it is safe and effective at relieving symptoms, with the goal of offering a less invasive alternative to surgery. The trial is currently recruiting 20 participants in Sweden.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
EUS-guided radiofrequency ablation (EUS-RFA)
What this could lead to
If it works, this could offer a less invasive treatment option for pancreatic insulinoma, potentially reducing symptoms and avoiding major surgery.
What could go wrong
This is a small, early-phase trial with only 20 participants. The procedure may not fully destroy the tumor, and there are risks like bleeding, infection, or pancreatitis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2025

Expected to finish

Jun 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patients referred to Sahlgrenska UH for the diagnosis and treatment of pancreatic insulinoma.

Ages

15 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Insulinoma verified by pathology (often from EUS-FNB-sampling) Exclusion Criteria: * Patients unwilling to participate * Patients unable to understand and obtain written informed conscent * Severe comorbidity

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Conditions

The condition(s) this trial relates to.

pancreatic insulinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Insulinoma; pancreas

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sahlgrenska Univeristy Hospital

    RECRUITING

    Gothenburg, Sweden

More trials for these conditions

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