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New heat therapy for pancreatic lesions tested in 100-Patient registry

NCT ID NCT07136324

Disease control Sponsor: The University of Texas Health Science Center, Houston Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tracks 100 people with pancreatic cysts or tumors who receive a treatment called endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA). A thin needle delivers heat directly to the lesion to destroy it. Researchers will monitor how well the procedure works and any side effects over 7 years. The goal is to see if this minimally invasive approach can be a safe alternative to surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
radiofrequency ablation (RFA) delivered via an endoscopic ultrasound-guided catheter
What this could lead to
If successful, this could show that EUS-guided RFA is a safe and effective way to treat pancreatic cysts and tumors without major surgery.
What could go wrong
This is an early-stage registry, not a controlled trial, so results may not prove effectiveness. There are also standard risks like bleeding, infection, or damage to nearby organs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Oct 2018

Expected to finish

Jul 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients who are undergoing EUS-RFA for the treatment of their pancreatic lesion(s).

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1\. Diagnosis of any pancreatic premalignant lesion and/or pancreatic malignancy Exclusion Criteria: 1. Patients with co-existing malignancies of other organs (or a prior history of such) 2. Patients unable to provide informed consent 3. Patients unable to complete follow-up

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm Pancreatic Cyst pancreatic neoplasm precancerous condition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pancreatic cyst

Contacts and locations

Locations

  • Memorial Hermann Hospital

    Houston, Texas, 77054, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.