Can a new imaging trick spot pancreatic cancer without a biopsy?
NCT ID NCT07763561
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This study looks at whether a special ultrasound technique called detective flow imaging (DFI) can help doctors tell the difference between benign and malignant solid pancreatic lesions. Researchers will examine the blood vessel patterns seen with this technique and compare them to the final diagnosis from tissue samples or follow-up. The study involves 48 adults with solid pancreatic lesions and aims to see if this imaging method is accurate and consistent between different doctors.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Endoscopic ultrasound-guided detective flow imaging (EUS-DFI), an imaging technique
- What this could lead to
- If successful, this imaging method could improve how doctors tell benign from malignant pancreatic lesions without invasive biopsies, leading to faster and more accurate diagnoses.
- What could go wrong
- This is an observational study with a small number of participants, so results may not apply broadly. The technique's accuracy depends on operator skill, and it may not clearly distinguish all tumor types.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients undergoing routine endoscopic ultrasound (EUS) in participating centers in whom a solid pancreatic lesion is identified and who provide written informed consent.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older. * Presence of a solid pancreatic lesion identified during endoscopic ultrasound (EUS), regardless of the indication for the examination. * Ability and willingness to provide written informed consent. Exclusion Criteria: * Predominantly cystic pancreatic lesions. * Anatomical abnormalities preventing adequate EUS examination. * Limited ability to understand the study procedures or provide informed consent. * Refusal to sign the informed consent form.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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