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New inhaled drug shows promise for cystic fibrosis in early trial

NCT ID NCT06478706

First seen Jan 05, 2026 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This study tested an inhaled drug called ETD001 in 57 adults with cystic fibrosis. The trial had two parts: one to check safety over 7 days, and another to see if the drug improves lung function over 28 days. Participants took the drug or a placebo twice daily. The goal is to find a new treatment that helps people with CF breathe easier.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • All Wales Adult CF Centre

    Cardiff, CF64 2XX, United Kingdom

  • Azienda Ospedaliera Universitaria Integrata Verona

    Verona, 37126, Italy

  • Azienda Ospedaliera Universitaria Meyer

    Florence, 50139, Italy

  • Belfast Health and Social Care Trust

    Belfast, BT9 7AB, United Kingdom

  • CF-Studienzentrum Universitätsklinikum Köln

    Cologne, 50924, Germany

  • CHU de Montpellier

    Montpellier, 34295, France

  • Charité Universtaetsmedizin

    Berlin, 13353, Germany

  • Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

    Milan, 20122, Italy

  • Hospices Civils de Lyon

    Lyon, 69495, France

  • Hôpital Cochin

    Paris, 75014, France

  • Hôpitaux de Toulouse

    Toulouse, 31059, France

  • IKF Pneumologie

    Frankfurt, 60596, Germany

  • IRCCS Istituto Giannina Gaslini

    Genova, 16147, Italy

  • LMU Kinikum

    Munich, 80336, Germany

  • Ospedale Pediatrico Bambino Gesù

    Roma, 00165, Italy

  • Queen Elizabeth University Hospital West of Scotland CF Service

    Glasgow, G51 4TR, United Kingdom

  • Royal Brompton Hospital

    London, SW3 6LL, United Kingdom

  • Royal Papworth Hospital

    Cambridge, CB2 0AY, United Kingdom

  • Southampton General Hospital

    Southampton, SO16 6YD, United Kingdom

  • Universitätsklinikum Frankfurt

    Frankfurt, 60590, Germany

  • Westdeutsches Lungenzentrum am Universitätsklinikum

    Essen, 45239, Germany

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ETD001 (inhaled drug)

What this could lead to

If successful, this could lead to a new inhaled treatment that improves lung function in people with cystic fibrosis.

What could go wrong

This is an early Phase 2 trial with only 57 participants, so results may not apply to everyone. The drug may not improve lung function or could cause side effects.

Conditions

The condition(s) this trial relates to.

cystic fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.