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Could estrogen exposure explain why some pituitary tumors grow larger?

NCT ID NCT07268183

First seen Jan 05, 2026

Summary

This study investigates whether higher lifetime exposure to estrogen—from sources like birth control, pregnancy, or hormone therapy—is linked to the development of larger prolactin-secreting pituitary tumors (macroprolactinomas) compared to smaller ones (microprolactinomas). Researchers will compare estrogen exposure histories in 180 women diagnosed with either type of tumor. The goal is to identify potential risk factors that might explain why some tumors grow larger.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Hopital Louis Pradel

    RECRUITING

    Bron, Rhone, 69500, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If this study finds a link, it could help doctors understand why some women develop larger prolactinomas and possibly guide future prevention or monitoring strategies.

What could go wrong

This is an observational study using questionnaires, so it cannot prove cause and effect. Results may be limited by recall bias or other unmeasured factors.

Conditions

The condition(s) this trial relates to.

Pituitary Neoplasms prolactin-producing pituitary gland adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.