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Nerve block or lidocaine drip: which eases breast cancer surgery pain better?

NCT ID NCT07108959

Symptom relief Sponsor: Alexandria University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compared two ways to manage pain during breast cancer surgery: a nerve block (erector spinae plane block) and a lidocaine drip given through a vein. Researchers measured inflammation markers and pain levels in 40 women undergoing surgery. The goal was to see which method better reduces inflammation and improves recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
lidocaine infusion and erector spinae plane block (nerve block procedure)
What this could lead to
If successful, this could point toward a better way to manage pain and inflammation during breast cancer surgery, potentially improving recovery.
What could go wrong
This is a small, completed study with only 40 participants, so results may not apply to all patients. The findings are preliminary and need confirmation in larger trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Aug 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 60 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 30 -60 years. * Female patients. * ASA physical status class I - II. * Elective resectable non metastatic breast cancer. Exclusion Criteria: * Patients with history of sensitivity to the studied drugs. * Patients with cardiac conduction defects. * Patients with major spine deformities. * Patients with severe coagulopathy. * Patients with infection at injection site. * Patients with preexisting myopathy or neuropathy because it can worsen neurological deficits and increase sensitivity to local anaesthetic toxicity. Additionally, it complicates diagnosis of new symptoms and carries higher medicolegal risk due to difficulty distinguishing anaesthesia effects from disease progression. * Psychiatric disease or seizure disorder requiring medication within the previous 2 years. * Opioid tolerant patient. * Cognitive dysfunction. * Body Mass Index ( BMI ) more than 35 kg/m2 or less than 18 kg/m2 .

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer ESPB Lidocaine infusion

Contacts and locations

Locations

  • Faculty of Medicine , Alexandria University

    Alexandria, Alexandria Governorate, 21526, Egypt

More trials for these conditions

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