New pain block may ease suffering after mastectomy
NCT ID NCT06533566
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two methods to control pain after a mastectomy: a nerve block in the back (erector spinae plane block) and numbing medicine injected into the wound. 37 women took part. The goal was to see which approach reduces pain and the need for morphine in the first day after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Erector spinae plane block (nerve block procedure) and local wound infiltration (injection of anesthetic into surgical site)
- What this could lead to
- If one method works better, it could help reduce pain and the need for strong painkillers after mastectomy.
- What could go wrong
- This is a small, completed study with only 37 participants, so results may not apply to everyone. Pain relief varies from person to person.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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37 people
The number who actually took part.
- Started
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Aug 2024
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * American Society of Anesthesiology (ASA) physical status I-II * scheduled for unilateral Modified radical mastectomy Exclusion Criteria: * Patient refusal. * Patient with neurological deficit. * Patient with bleeding disorders. * Uncooperative patient. * Infection at the block injection site. * Patients with history of allergy to local anesthetics. * Advanced hepatic, cardiac or renal failure. * Chronic opioid consumption. * Body mass index (BMI)≥ 30 kg m-2 * Chronic use of gabapentin or pregabalin
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of medicine, Tanta university
Tanta, El Gharbyia, 31111, Egypt
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