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Can a new nerve block ease pain after lung surgery?

NCT ID NCT03176667

Symptom relief Sponsor: McMaster University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This pilot trial is testing whether an ultrasound-guided erector spinae plane (ESP) block can control pain after video-assisted thoracoscopic surgery (VATS) for lung procedures. It compares the ESP block to the standard intercostal nerve block, both combined with patient-controlled analgesia. The study includes 20 adults undergoing elective VATS lobectomy or wedge resection. The main goal is to see if the ESP block is feasible and safe, while also measuring pain scores and nerve blockage coverage.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ultrasound-guided erector spinae plane (ESP) block, a nerve block procedure
What this could lead to
If successful, this could lead to a better, less painful recovery option for people undergoing lung surgery.
What could go wrong
This is a small pilot study, so results may not be definitive. The ESP block may not provide better pain relief than the standard approach, and there are risks like bleeding or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Dec 2018

Finished

Apr 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Elective video-assisted thoracoscopic surgeries (VATS) lobectomies * Elective video-assisted thoracoscopic surgeries (VATS) wedge resections Exclusion Criteria: * Patient refusal * Contraindications to regional anesthesia * Known allergy to local anesthetics * Bleeding diathesis * Use of any anti-coagulants * Inability to provide informed consent * Severe kidney or liver disease * Inability to operate PCA system

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post operative pain

Contacts and locations

Locations

  • St. Joseph's Healthcare Hamilton

    Hamilton, Ontario, L8N 4A6, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.