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New combo treatment aims to quiet suicidal thoughts fast

NCT ID NCT07396220

First seen Feb 16, 2026 · Last updated May 18, 2026 · Updated 11 times

Summary

This study tests whether a nasal spray (esketamine) combined with a short therapy program can quickly reduce suicidal thoughts in people with hard-to-treat depression. About 56 adults aged 18-70 with ongoing suicidal thoughts will receive either the combo treatment or esketamine alone. The goal is to see if adding therapy leads to a greater drop in suicidal thinking after one week.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UC San Diego Health - 4S Ranch

    San Diego, California, 92127, United States

Conditions

Explore the condition pages connected to this study.