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Could a nasal spray boost PTSD therapy? small study explores the idea

NCT ID NCT06795659

First seen Jan 29, 2026 · Last updated May 01, 2026 · Updated 11 times

Summary

This early-phase study tested whether adding esketamine (a nasal spray approved for depression) to prolonged exposure therapy could help reduce PTSD symptoms. Only 4 adults with PTSD took part. The main goal was to see if the combination was feasible and acceptable, not to prove it works. Results are limited due to the very small size.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • The University of Texas Health Science Center at San Antonio

    San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.