Nerve block or local injection: which eases mastectomy pain better?
NCT ID NCT06533566
First seen Dec 17, 2025 · Last updated Jun 19, 2026 · Updated 30 times
Summary
This study compared two ways to manage pain after modified radical mastectomy: an ultrasound-guided nerve block (erector spinae plane block) versus injecting anesthetic into the surgical wound. Thirty-seven women participated, and researchers measured how much morphine they needed in the first day after surgery. The goal is to find which method provides better pain relief and reduces reliance on strong opioids.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Faculty of medicine, Tanta university
Tanta, El Gharbyia, 31111, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Erector spinae plane block (nerve block procedure) and local wound infiltration (injection of anesthetic into surgical site)
What this could lead to
If one method works better, it could help reduce pain and the need for strong painkillers after mastectomy.
What could go wrong
This is a small, completed study with only 37 participants. Results may not apply to all patients, and both methods carry risks like infection or allergic reaction.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.