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Could a simple nerve block shield kidneys during cancer surgery?

NCT ID NCT07297433

Knowledge-focused Sponsor: Kayseri City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a nerve block called the erector spinae plane block can protect kidney function during laparoscopic colorectal cancer surgery. Sixty adults having this surgery were divided into two groups: one received the nerve block plus standard anesthesia, the other received only standard anesthesia. Researchers measured kidney blood flow during surgery and checked kidney function afterward using blood tests and a special protein called NGAL. The goal was to see if the nerve block helps keep kidneys working well during and after the operation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Erector spinae plane block (a nerve block injection)
What this could lead to
If successful, this could show that using this nerve block during surgery helps protect kidney function, potentially reducing the risk of kidney injury after colorectal cancer surgery.
What could go wrong
This is a small, completed study with only 60 participants, so results may not apply to everyone. It measures temporary changes in kidney function, not long-term outcomes or survival.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Jan 2025

Finished

Apr 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age: 35-75 years old * Colorectal cancer surgery must be planned by a physician * No infection in the injection site * No history of any disease related to clotting or bleeding time * The patient must be a volunteer * No history of local anesthetic allergy Exclusion Criteria: * Being under 18 years of age * Having a systemic infection or infection at the injection site * Having any disease related to bleeding time and clotting * Having a history of local anesthetic allergy * Patient refusal (ESPB for analgesic purposes) * Patients with a Body Mass Index (BMI) of 30 or above

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Conditions

The condition(s) this trial relates to.

colon carcinoma colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Kolon kanseri

Contacts and locations

Locations

  • Kayseri Şehir Hastanesi

    Kayseri, 38080, Turkey (Türkiye)