Can a back nerve block replace opioids for kidney stone pain?
NCT ID NCT07067996
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
This trial tests whether a nerve block called the erector spinae plane block can better control pain during extracorporeal shock wave lithotripsy (ESWL), a common procedure to break up kidney stones. Sixty adults with 2-3 cm kidney stones will receive either the nerve block or a standard painkiller (nalbuphine). Researchers will measure pain levels using a standard 0-10 scale to see which approach works better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a nerve block called erector spinae plane block, compared to the painkiller nalbuphine
- What this could lead to
- If it works, this could offer a more effective way to manage pain during kidney stone treatment without relying solely on opioids.
- What could go wrong
- This is a small, early-stage trial with only 60 participants. The nerve block may not provide better pain relief than standard medication and carries risks like infection or bleeding.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Jun 2025
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult Patients undergoing ESWL with 2-3 cm renal stones * patients between the ages of 21 and 60, * both sexes, * BMI ≥18≤30 kg/m² * Able to give informed consent. * Patients older than 18 years with American Society of Anesthesiologists Physical Status I or II and Exclusion Criteria: * Coagulopathy or on anticoagulants * Infection at the ESPB injection site * BMI ≥30 kg/m² * Patient refusal. * patients with advanced respiratory, renal, hepatic, neurological, or psychiatric disease, pregnant or nursing women. * patients with a history of allergies to any study drugs
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sohag University Hospital
Sohag, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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