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New registry aims to unlock mysteries of rare histiocyte disorders

NCT ID NCT03329274

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 36 times

Summary

This study creates a registry for people with Erdheim-Chester disease and related histiocytoses. Researchers will collect medical information and patient experiences over time to better understand these rare conditions. Up to 500 participants will be enrolled, and some may be asked to complete a brief phone interview. The goal is to capture comprehensive data on symptoms, treatments, and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this registry could help doctors better understand how histiocytoses progress and respond to treatments, potentially guiding future care.

What could go wrong

This is an observational registry, not a treatment trial. It will not directly test any new therapy, so it may not lead to immediate changes in care.

Conditions

The condition(s) this trial relates to.

Erdheim-Chester disease histiocytic and dendritic cell neoplasm Histiocytosis, Langerhans-Cell Langerhans cell histiocytosis sinus histiocytosis with massive lymphadenopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.