Could a simple pill combo prevent heart attacks and amputations?
NCT ID NCT06930885
First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 28 times
Summary
This study tests whether a daily polypill (combining several heart medications) plus colchicine can reduce major heart problems, strokes, and limb loss in people with established heart or artery disease. About 7,700 to 10,800 adults aged 45 and older who have had a heart attack, stroke, or artery procedure will take part. The goal is to see if this combination is better than standard care at preventing serious events.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CIPES - Centro Internacional de Pesquisa Clínica
RECRUITINGSão José dos Campos, São Paulo, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CMEP - Centro Multidisciplinar de Ensino especializado e Pesquisa
RECRUITINGJoinville, Santa Catarina, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centro de Pesquisa Cardiolima
RECRUITINGTeresina, Piauí, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centro de Pesquisa Cetrus
RECRUITINGSão Paulo, São Paulo, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centro de Pesquisas Clínicas Dr. Marco Mota
RECRUITINGMaceió, Alabama, 57051160, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Empresa Brasileira de Serviços Hospitalares - EBSERCH - Hospital de Ensino Dr. Washington Antônio de Barros- HU-UNIVASF
RECRUITINGPetrolina, Pernambuco, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fundação Faculdade Regional de Medicina São José do Rio Preto
RECRUITINGSão José do Rio Preto, São Paulo, 15.090-000, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fundação Técnico Educacional Souza Marques
RECRUITINGRio de Janeiro, Rio de Janeiro, 22.793-140, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fundação Universitária de Cardiologia - ICFUC
RECRUITINGPorto Alegre, Rio Grande do Sul, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hcor
RECRUITINGSão Paulo, São Paulo, 04004-030, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitário São Francisco na Providência de Deus
RECRUITINGBragança Paulista, São Paulo, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Instituto de Pesquisa e Ensino em Saúde - IPES
RECRUITINGPorto Velho, Rondônia, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Secretária da Saúde do Estado do Ceará - Hospital de Messejana Dr. Carlos Alberto Studart Gomes
RECRUITINGMessejana, Ceará, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.