Study probes Epinephrine's role in blood vessel health
NCT ID NCT02692313
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 30 times
Summary
This completed early-phase study looked at how epinephrine (adrenaline) affects blood vessel function and clotting in 32 healthy adults. Researchers gave participants epinephrine or a placebo and measured changes in artery dilation. The goal was to better understand why people with diabetes face higher heart risks, but the study did not involve diabetes patients.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Maryland, Baltimore
Baltimore, Maryland, 21201, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Epinephrine (adrenaline)
What this could lead to
If successful, this study could help explain how the body's response to low blood sugar affects blood vessels, potentially pointing toward ways to prevent heart problems in people with diabetes.
What could go wrong
This is a very early study in only 32 healthy people, not those with diabetes. It measures temporary changes in blood vessel function, not long-term health outcomes, so results may not apply to real-world diabetes care.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.