Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could bacteria be causing your back pain? new study investigates

NCT ID NCT03406624

Knowledge-focused Sponsor: Oslo University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study from Oslo University Hospital looked for bacteria in the discs and bones of 200 people with chronic low back pain who were having spine surgery. Researchers took tissue samples during surgery and used lab tests and genetic sequencing to detect any bacteria. The goal was to better understand if bacteria are linked to certain spine changes seen on MRI, which could lead to new ways to diagnose or treat back pain in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help identify whether bacteria play a role in chronic low back pain, potentially pointing toward new diagnostic or treatment approaches.
What could go wrong
This is an observational study focused on understanding, not testing a treatment. Results may not lead to direct patient benefits, and findings could be due to contamination rather than true infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

200 people

The number who actually took part.

Started

Jan 2018

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients will be recruited from orthopaedic outpatient clinics at four university hospitals. They will be asked for participation after being scheduled for surgery with lumbar spinal fusion with procedures involving moderate to extensive removal of the disc (i.e. transforaminal lumbar interbody fusion (TLIF), posterior Lumbar Interbody Fusion (PLIF)) or or disc herniation surgery.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients scheduled for surgery with lumbar spinal fusion with procedures involving moderate to extensive removal of the disc or disc herniation surgery (for cases: MC seen on MRI at the actual level for surgery, for controls: no MC seen on MRI at the actual level for surgery) * LBP in the area below the 12th rib and above the gluteal folds * Age \> 18 years * Written informed consent Exclusion Criteria: * Antibiotic treatment within the preceding one month before surgery * Use of glucocorticoids the preceding month before surgery * Small dots (i.e. \<= 5 mm or height \<10% of vertebra) are not included for any cases or control group * Unwilling to participate * Contraindications to MRI

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Low back pain are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Low Back Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Low back pain

Contacts and locations

Locations

  • Akershus University Hospital

    Lørenskog, Lørenskog, 1478, Norway

  • Haukeland University Hospital

    Bergen, Bergen, 5021, Norway

  • Oslo University Hospital Ullevål

    Oslo, Oslo, 4950, Norway

  • Stavanger Universitetssjukehus

    Stavanger, Norway

More trials for these conditions

Other studies related to the condition(s) this trial covers.